Resume and JobRESUME AND JOB
Amgen logo

Principal Agentic AI Chatbot Engineer

Amgen

Principal Agentic AI Chatbot Engineer

Amgen logo

Amgen

full-time

Posted: November 12, 2025

Number of Vacancies: 1

Job Description

Join Amgen’s Mission of Serving Patients

What you will do

  • Own the enterprise agent/bot platform architecture (cloud/on-prem), API contracts, and guardrails for multi-tenant use
  • Design and ship production agentic systems: multi-agent planning, tool/function calling, workflow orchestration, and structured outputs
  • Build high-containment bots for web/mobile/Slack/Teams/IVR with streaming responses and sub-second turn latency where required
  • Implement retrieval & memory (RAG, vector stores, knowledge graphs, session memory) with data contracts, lineage, and lifecycle governance
  • Establish bot CI/CD: prompt & config versioning, replay/conversation tests, feature flags, and automated rollbacks. Implement progressive delivery (blue-green, canary) with health checks, feature flags, and one-click rollback
  • Stand up observability: tracing, metrics, and conversation analytics (containment, escalation, hallucination, CSAT, latency, cost per turn) with alerts and runbooks
  • Integrate securely with enterprise systems (e.g., SAP, Salesforce, ServiceNow, MES/LIMS/ELN/QMS) via robust connectors and least-privilege tool access
  • Embed safety, privacy, and compliance (content filtering, red-teaming, audit trails, secrets mgmt) aligned to GxP/21 CFR Part 11 and HIPAA/PII needs
  • Optimize inference and cost (routing, caching, batching, distillation/quantization) and drive GPU/accelerator/FinOps strategy
  • Evaluate and document trade-offs for models (open vs. proprietary), hosting options, and agent frameworks (e.g., LangChain, Semantic Kernel, Assistants APIs)
  • Translate domain needs (R&D, Manufacturing, Commercial) into prioritized roadmaps; mentor teams and communicate technical trade-offs to stakeholders

What we expect of you

  • Doctorate degree and 2 years of Computer Science, IT or related field experience
  • Or Master’s degree and 4 years of Computer Science, IT or related field experience
  • Or Bachelor’s degree and 6 years of Computer Science, IT or related field experience
  • Or Associate’s degree and 10 years of Computer Science, IT or related field experience
  • Or High school diploma / GED and 12 years of Computer Science, IT or related field experience
  • Preferred: 3-5 years in AI/ML and enterprise software
  • Knowledge graphs or structured reasoning (SPARQL, RDF/OWL) and tool-use planning with constraints
  • Safety tooling (jailbreak detection, content moderation, PII redaction) and automated red-team pipelines
  • Experience with privacy-preserving patterns (data masking, synthetic data, federated or on-prem inference)
  • Domain familiarity in biopharma workflows (clinical operations, quality, manufacturing/supply chain, field/commercial)
  • FinOps at scale: GPU fleet planning, utilization dashboards, commitment management
  • Contributions to open source in LLM/agent ecosystems; patents or publications in conversational AI
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives
  • Good-to-Have: Experience in Biotechnology or pharma industry
  • Published thought-leadership or conference talks on enterprise GenAI adoption
  • Master’s degree in Computer Science and or Data Science
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.)

Must-Have Skills

  • Excellent analytical and troubleshooting skills
  • Strong verbal and written communication skills
  • Ability to work effectively with global, virtual teams
  • High degree of initiative and self-motivation
  • Ability to manage multiple priorities successfully
  • Team-oriented, with a focus on achieving team goals
  • Ability to learn quickly, be organized and detail oriented
  • Strong presentation and public speaking skills

What you can expect of us

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
  • Group medical, dental and vision coverage
  • Life and disability insurance
  • Flexible spending accounts
  • Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models, including remote and hybrid work arrangements, where possible

Compensation

3-5

Locations

  • Thousand Oaks, United States of America (Remote)

Salary

Salary not disclosed

Estimated Salary Rangehigh confidence

180,000 - 220,000 USD / yearly

Source: xAI estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Excellent analytical and troubleshooting skillsintermediate
  • Strong verbal and written communication skillsintermediate
  • Ability to work effectively with global, virtual teamsintermediate
  • High degree of initiative and self-motivationintermediate
  • Ability to manage multiple priorities successfullyintermediate
  • Team-oriented, with a focus on achieving team goalsintermediate
  • Ability to learn quickly, be organized and detail orientedintermediate
  • Strong presentation and public speaking skillsintermediate

Required Qualifications

  • Doctorate degree and 2 years of Computer Science, IT or related field experience (experience)
  • Or Master’s degree and 4 years of Computer Science, IT or related field experience (experience)
  • Or Bachelor’s degree and 6 years of Computer Science, IT or related field experience (experience)
  • Or Associate’s degree and 10 years of Computer Science, IT or related field experience (experience)
  • Or High school diploma / GED and 12 years of Computer Science, IT or related field experience (experience)
  • Preferred: 3-5 years in AI/ML and enterprise software (experience)
  • Knowledge graphs or structured reasoning (SPARQL, RDF/OWL) and tool-use planning with constraints (experience)
  • Safety tooling (jailbreak detection, content moderation, PII redaction) and automated red-team pipelines (experience)
  • Experience with privacy-preserving patterns (data masking, synthetic data, federated or on-prem inference) (experience)
  • Domain familiarity in biopharma workflows (clinical operations, quality, manufacturing/supply chain, field/commercial) (experience)
  • FinOps at scale: GPU fleet planning, utilization dashboards, commitment management (experience)
  • Contributions to open source in LLM/agent ecosystems; patents or publications in conversational AI (experience)
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives (experience)
  • Good-to-Have: Experience in Biotechnology or pharma industry (experience)
  • Published thought-leadership or conference talks on enterprise GenAI adoption (experience)
  • Master’s degree in Computer Science and or Data Science (experience)
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery (experience)
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) (experience)

Responsibilities

  • Own the enterprise agent/bot platform architecture (cloud/on-prem), API contracts, and guardrails for multi-tenant use
  • Design and ship production agentic systems: multi-agent planning, tool/function calling, workflow orchestration, and structured outputs
  • Build high-containment bots for web/mobile/Slack/Teams/IVR with streaming responses and sub-second turn latency where required
  • Implement retrieval & memory (RAG, vector stores, knowledge graphs, session memory) with data contracts, lineage, and lifecycle governance
  • Establish bot CI/CD: prompt & config versioning, replay/conversation tests, feature flags, and automated rollbacks. Implement progressive delivery (blue-green, canary) with health checks, feature flags, and one-click rollback
  • Stand up observability: tracing, metrics, and conversation analytics (containment, escalation, hallucination, CSAT, latency, cost per turn) with alerts and runbooks
  • Integrate securely with enterprise systems (e.g., SAP, Salesforce, ServiceNow, MES/LIMS/ELN/QMS) via robust connectors and least-privilege tool access
  • Embed safety, privacy, and compliance (content filtering, red-teaming, audit trails, secrets mgmt) aligned to GxP/21 CFR Part 11 and HIPAA/PII needs
  • Optimize inference and cost (routing, caching, batching, distillation/quantization) and drive GPU/accelerator/FinOps strategy
  • Evaluate and document trade-offs for models (open vs. proprietary), hosting options, and agent frameworks (e.g., LangChain, Semantic Kernel, Assistants APIs)
  • Translate domain needs (R&D, Manufacturing, Commercial) into prioritized roadmaps; mentor teams and communicate technical trade-offs to stakeholders

Benefits

  • general: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
  • general: Group medical, dental and vision coverage
  • general: Life and disability insurance
  • general: Flexible spending accounts
  • general: Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • general: Stock-based long-term incentives
  • general: Award-winning time-off plans
  • general: Flexible work models, including remote and hybrid work arrangements, where possible

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Amgen logo

Principal Agentic AI Chatbot Engineer

Amgen

Principal Agentic AI Chatbot Engineer

Amgen logo

Amgen

full-time

Posted: November 12, 2025

Number of Vacancies: 1

Job Description

Join Amgen’s Mission of Serving Patients

What you will do

  • Own the enterprise agent/bot platform architecture (cloud/on-prem), API contracts, and guardrails for multi-tenant use
  • Design and ship production agentic systems: multi-agent planning, tool/function calling, workflow orchestration, and structured outputs
  • Build high-containment bots for web/mobile/Slack/Teams/IVR with streaming responses and sub-second turn latency where required
  • Implement retrieval & memory (RAG, vector stores, knowledge graphs, session memory) with data contracts, lineage, and lifecycle governance
  • Establish bot CI/CD: prompt & config versioning, replay/conversation tests, feature flags, and automated rollbacks. Implement progressive delivery (blue-green, canary) with health checks, feature flags, and one-click rollback
  • Stand up observability: tracing, metrics, and conversation analytics (containment, escalation, hallucination, CSAT, latency, cost per turn) with alerts and runbooks
  • Integrate securely with enterprise systems (e.g., SAP, Salesforce, ServiceNow, MES/LIMS/ELN/QMS) via robust connectors and least-privilege tool access
  • Embed safety, privacy, and compliance (content filtering, red-teaming, audit trails, secrets mgmt) aligned to GxP/21 CFR Part 11 and HIPAA/PII needs
  • Optimize inference and cost (routing, caching, batching, distillation/quantization) and drive GPU/accelerator/FinOps strategy
  • Evaluate and document trade-offs for models (open vs. proprietary), hosting options, and agent frameworks (e.g., LangChain, Semantic Kernel, Assistants APIs)
  • Translate domain needs (R&D, Manufacturing, Commercial) into prioritized roadmaps; mentor teams and communicate technical trade-offs to stakeholders

What we expect of you

  • Doctorate degree and 2 years of Computer Science, IT or related field experience
  • Or Master’s degree and 4 years of Computer Science, IT or related field experience
  • Or Bachelor’s degree and 6 years of Computer Science, IT or related field experience
  • Or Associate’s degree and 10 years of Computer Science, IT or related field experience
  • Or High school diploma / GED and 12 years of Computer Science, IT or related field experience
  • Preferred: 3-5 years in AI/ML and enterprise software
  • Knowledge graphs or structured reasoning (SPARQL, RDF/OWL) and tool-use planning with constraints
  • Safety tooling (jailbreak detection, content moderation, PII redaction) and automated red-team pipelines
  • Experience with privacy-preserving patterns (data masking, synthetic data, federated or on-prem inference)
  • Domain familiarity in biopharma workflows (clinical operations, quality, manufacturing/supply chain, field/commercial)
  • FinOps at scale: GPU fleet planning, utilization dashboards, commitment management
  • Contributions to open source in LLM/agent ecosystems; patents or publications in conversational AI
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives
  • Good-to-Have: Experience in Biotechnology or pharma industry
  • Published thought-leadership or conference talks on enterprise GenAI adoption
  • Master’s degree in Computer Science and or Data Science
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.)

Must-Have Skills

  • Excellent analytical and troubleshooting skills
  • Strong verbal and written communication skills
  • Ability to work effectively with global, virtual teams
  • High degree of initiative and self-motivation
  • Ability to manage multiple priorities successfully
  • Team-oriented, with a focus on achieving team goals
  • Ability to learn quickly, be organized and detail oriented
  • Strong presentation and public speaking skills

What you can expect of us

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
  • Group medical, dental and vision coverage
  • Life and disability insurance
  • Flexible spending accounts
  • Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models, including remote and hybrid work arrangements, where possible

Compensation

3-5

Locations

  • Thousand Oaks, United States of America (Remote)

Salary

Salary not disclosed

Estimated Salary Rangehigh confidence

180,000 - 220,000 USD / yearly

Source: xAI estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Excellent analytical and troubleshooting skillsintermediate
  • Strong verbal and written communication skillsintermediate
  • Ability to work effectively with global, virtual teamsintermediate
  • High degree of initiative and self-motivationintermediate
  • Ability to manage multiple priorities successfullyintermediate
  • Team-oriented, with a focus on achieving team goalsintermediate
  • Ability to learn quickly, be organized and detail orientedintermediate
  • Strong presentation and public speaking skillsintermediate

Required Qualifications

  • Doctorate degree and 2 years of Computer Science, IT or related field experience (experience)
  • Or Master’s degree and 4 years of Computer Science, IT or related field experience (experience)
  • Or Bachelor’s degree and 6 years of Computer Science, IT or related field experience (experience)
  • Or Associate’s degree and 10 years of Computer Science, IT or related field experience (experience)
  • Or High school diploma / GED and 12 years of Computer Science, IT or related field experience (experience)
  • Preferred: 3-5 years in AI/ML and enterprise software (experience)
  • Knowledge graphs or structured reasoning (SPARQL, RDF/OWL) and tool-use planning with constraints (experience)
  • Safety tooling (jailbreak detection, content moderation, PII redaction) and automated red-team pipelines (experience)
  • Experience with privacy-preserving patterns (data masking, synthetic data, federated or on-prem inference) (experience)
  • Domain familiarity in biopharma workflows (clinical operations, quality, manufacturing/supply chain, field/commercial) (experience)
  • FinOps at scale: GPU fleet planning, utilization dashboards, commitment management (experience)
  • Contributions to open source in LLM/agent ecosystems; patents or publications in conversational AI (experience)
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives (experience)
  • Good-to-Have: Experience in Biotechnology or pharma industry (experience)
  • Published thought-leadership or conference talks on enterprise GenAI adoption (experience)
  • Master’s degree in Computer Science and or Data Science (experience)
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery (experience)
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) (experience)

Responsibilities

  • Own the enterprise agent/bot platform architecture (cloud/on-prem), API contracts, and guardrails for multi-tenant use
  • Design and ship production agentic systems: multi-agent planning, tool/function calling, workflow orchestration, and structured outputs
  • Build high-containment bots for web/mobile/Slack/Teams/IVR with streaming responses and sub-second turn latency where required
  • Implement retrieval & memory (RAG, vector stores, knowledge graphs, session memory) with data contracts, lineage, and lifecycle governance
  • Establish bot CI/CD: prompt & config versioning, replay/conversation tests, feature flags, and automated rollbacks. Implement progressive delivery (blue-green, canary) with health checks, feature flags, and one-click rollback
  • Stand up observability: tracing, metrics, and conversation analytics (containment, escalation, hallucination, CSAT, latency, cost per turn) with alerts and runbooks
  • Integrate securely with enterprise systems (e.g., SAP, Salesforce, ServiceNow, MES/LIMS/ELN/QMS) via robust connectors and least-privilege tool access
  • Embed safety, privacy, and compliance (content filtering, red-teaming, audit trails, secrets mgmt) aligned to GxP/21 CFR Part 11 and HIPAA/PII needs
  • Optimize inference and cost (routing, caching, batching, distillation/quantization) and drive GPU/accelerator/FinOps strategy
  • Evaluate and document trade-offs for models (open vs. proprietary), hosting options, and agent frameworks (e.g., LangChain, Semantic Kernel, Assistants APIs)
  • Translate domain needs (R&D, Manufacturing, Commercial) into prioritized roadmaps; mentor teams and communicate technical trade-offs to stakeholders

Benefits

  • general: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
  • general: Group medical, dental and vision coverage
  • general: Life and disability insurance
  • general: Flexible spending accounts
  • general: Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • general: Stock-based long-term incentives
  • general: Award-winning time-off plans
  • general: Flexible work models, including remote and hybrid work arrangements, where possible

Target Your Resume for "Principal Agentic AI Chatbot Engineer" , Amgen

Get personalized recommendations to optimize your resume specifically for Principal Agentic AI Chatbot Engineer. Takes only 15 seconds!

AI-powered keyword optimization
Skills matching & gap analysis
Experience alignment suggestions

Check Your ATS Score for "Principal Agentic AI Chatbot Engineer" , Amgen

Find out how well your resume matches this job's requirements. Get comprehensive analysis including ATS compatibility, keyword matching, skill gaps, and personalized recommendations.

ATS compatibility check
Keyword optimization analysis
Skill matching & gap identification
Format & readability score

Tags & Categories

Software EngineeringCloudFull StackInformation SystemsTechnology

Related Jobs You May Like

No related jobs found at the moment.