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Amgen logo

Principal IS Architect – Clinical Computation Platform

Amgen

Principal IS Architect – Clinical Computation Platform

Amgen logo

Amgen

full-time

Posted: November 12, 2025

Number of Vacancies: 1

Job Description

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

What you will do

  • Develop and maintain the enterprise architecture vision and strategy, ensuring alignment with business objectives
  • Create and maintain architectural roadmaps that guide the evolution of IT systems and capabilities
  • Establish and enforce architectural standards, policies, and governance frameworks
  • Evaluate emerging technologies and assess their potential impact on the enterprise/domain/solution architecture
  • Identify and mitigate architectural risks, ensuring that IT systems are scalable, secure, and resilient
  • Maintain comprehensive documentation of the architecture, including principles, standards, and models
  • Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
  • Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
  • Evaluate and recommend technologies and tools that best fit the solution requirements
  • Ensure seamless integration between systems and platforms, both within the organization and with external partners
  • Design systems that can scale to meet growing business needs and performance demands
  • Develop and maintain logical, physical, and conceptual data models to support business needs
  • Establish and enforce data standards, governance policies, and best practices
  • Design and manage metadata structures to enhance information retrieval and usability

What we expect of you

  • Master’s degree with 8 to 10 years of experience in Computer Science, IT or related field OR
  • Bachelor’s degree with 10 to 14 years of experience Computer Science, IT or related field OR
  • Diploma with 14 to 18 years of experience Computer Science, IT or related field
  • Proficiency in designing scalable, secure, and cost-effective solutions
  • Expertise in cloud platforms (AWS, Azure, GCP), data lakes, and data warehouses
  • Experience in evaluating and selecting technology vendors
  • Ability to create and demonstrate proof of concept solutions to validate technical feasibility
  • Strong knowledge of Clinical Research and Development Domain
  • Experience working in agile methodology, including Product Teams and Product Development models

Must-Have Skills

  • Strong solution design and problem-solving skills
  • Experience in developing differentiated and deliverable solutions
  • Ability to analyze client requirements and translate them into solutions
  • Experience with machine learning and artificial intelligence applications in clinical research
  • Strong programming skills in languages such as Python, R, or Java
  • Experience of DevOps, Continuous Integration, and Continuous Delivery methodology
  • Excellent critical-thinking and problem-solving skills
  • Demonstrated awareness of how to function in a team setting
  • Demonstrated awareness of presentation skills

Good-to-Have Skills

  • Good communication and collaboration skills

What you can expect of us

  • Competitive benefits
  • Collaborative culture
  • Support for professional and personal growth and well-being
  • Competitive and comprehensive Total Rewards Plans that are aligned with local industry standards

Locations

  • Hyderabad, India

Salary

Salary not disclosed

Estimated Salary Rangehigh confidence

80,000 - 120,000 USD / yearly

Source: xAI estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Strong solution design and problem-solving skillsintermediate
  • Experience in developing differentiated and deliverable solutionsintermediate
  • Ability to analyze client requirements and translate them into solutionsintermediate
  • Experience with machine learning and artificial intelligence applications in clinical researchintermediate
  • Strong programming skills in languages such as Python, R, or Javaintermediate
  • Experience of DevOps, Continuous Integration, and Continuous Delivery methodologyintermediate
  • Excellent critical-thinking and problem-solving skillsintermediate
  • Good communication and collaboration skillsintermediate
  • Demonstrated awareness of how to function in a team settingintermediate
  • Demonstrated awareness of presentation skillsintermediate

Required Qualifications

  • Master’s degree with 8 to 10 years of experience in Computer Science, IT or related field OR (experience)
  • Bachelor’s degree with 10 to 14 years of experience Computer Science, IT or related field OR (experience)
  • Diploma with 14 to 18 years of experience Computer Science, IT or related field (experience)
  • Proficiency in designing scalable, secure, and cost-effective solutions (experience)
  • Expertise in cloud platforms (AWS, Azure, GCP), data lakes, and data warehouses (experience)
  • Experience in evaluating and selecting technology vendors (experience)
  • Ability to create and demonstrate proof of concept solutions to validate technical feasibility (experience)
  • Strong knowledge of Clinical Research and Development Domain (experience)
  • Experience working in agile methodology, including Product Teams and Product Development models (experience)

Responsibilities

  • Develop and maintain the enterprise architecture vision and strategy, ensuring alignment with business objectives
  • Create and maintain architectural roadmaps that guide the evolution of IT systems and capabilities
  • Establish and enforce architectural standards, policies, and governance frameworks
  • Evaluate emerging technologies and assess their potential impact on the enterprise/domain/solution architecture
  • Identify and mitigate architectural risks, ensuring that IT systems are scalable, secure, and resilient
  • Maintain comprehensive documentation of the architecture, including principles, standards, and models
  • Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
  • Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
  • Evaluate and recommend technologies and tools that best fit the solution requirements
  • Ensure seamless integration between systems and platforms, both within the organization and with external partners
  • Design systems that can scale to meet growing business needs and performance demands
  • Develop and maintain logical, physical, and conceptual data models to support business needs
  • Establish and enforce data standards, governance policies, and best practices
  • Design and manage metadata structures to enhance information retrieval and usability

Benefits

  • general: Competitive benefits
  • general: Collaborative culture
  • general: Support for professional and personal growth and well-being
  • general: Competitive and comprehensive Total Rewards Plans that are aligned with local industry standards

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Amgen logo

Principal IS Architect – Clinical Computation Platform

Amgen

Principal IS Architect – Clinical Computation Platform

Amgen logo

Amgen

full-time

Posted: November 12, 2025

Number of Vacancies: 1

Job Description

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

What you will do

  • Develop and maintain the enterprise architecture vision and strategy, ensuring alignment with business objectives
  • Create and maintain architectural roadmaps that guide the evolution of IT systems and capabilities
  • Establish and enforce architectural standards, policies, and governance frameworks
  • Evaluate emerging technologies and assess their potential impact on the enterprise/domain/solution architecture
  • Identify and mitigate architectural risks, ensuring that IT systems are scalable, secure, and resilient
  • Maintain comprehensive documentation of the architecture, including principles, standards, and models
  • Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
  • Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
  • Evaluate and recommend technologies and tools that best fit the solution requirements
  • Ensure seamless integration between systems and platforms, both within the organization and with external partners
  • Design systems that can scale to meet growing business needs and performance demands
  • Develop and maintain logical, physical, and conceptual data models to support business needs
  • Establish and enforce data standards, governance policies, and best practices
  • Design and manage metadata structures to enhance information retrieval and usability

What we expect of you

  • Master’s degree with 8 to 10 years of experience in Computer Science, IT or related field OR
  • Bachelor’s degree with 10 to 14 years of experience Computer Science, IT or related field OR
  • Diploma with 14 to 18 years of experience Computer Science, IT or related field
  • Proficiency in designing scalable, secure, and cost-effective solutions
  • Expertise in cloud platforms (AWS, Azure, GCP), data lakes, and data warehouses
  • Experience in evaluating and selecting technology vendors
  • Ability to create and demonstrate proof of concept solutions to validate technical feasibility
  • Strong knowledge of Clinical Research and Development Domain
  • Experience working in agile methodology, including Product Teams and Product Development models

Must-Have Skills

  • Strong solution design and problem-solving skills
  • Experience in developing differentiated and deliverable solutions
  • Ability to analyze client requirements and translate them into solutions
  • Experience with machine learning and artificial intelligence applications in clinical research
  • Strong programming skills in languages such as Python, R, or Java
  • Experience of DevOps, Continuous Integration, and Continuous Delivery methodology
  • Excellent critical-thinking and problem-solving skills
  • Demonstrated awareness of how to function in a team setting
  • Demonstrated awareness of presentation skills

Good-to-Have Skills

  • Good communication and collaboration skills

What you can expect of us

  • Competitive benefits
  • Collaborative culture
  • Support for professional and personal growth and well-being
  • Competitive and comprehensive Total Rewards Plans that are aligned with local industry standards

Locations

  • Hyderabad, India

Salary

Salary not disclosed

Estimated Salary Rangehigh confidence

80,000 - 120,000 USD / yearly

Source: xAI estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Strong solution design and problem-solving skillsintermediate
  • Experience in developing differentiated and deliverable solutionsintermediate
  • Ability to analyze client requirements and translate them into solutionsintermediate
  • Experience with machine learning and artificial intelligence applications in clinical researchintermediate
  • Strong programming skills in languages such as Python, R, or Javaintermediate
  • Experience of DevOps, Continuous Integration, and Continuous Delivery methodologyintermediate
  • Excellent critical-thinking and problem-solving skillsintermediate
  • Good communication and collaboration skillsintermediate
  • Demonstrated awareness of how to function in a team settingintermediate
  • Demonstrated awareness of presentation skillsintermediate

Required Qualifications

  • Master’s degree with 8 to 10 years of experience in Computer Science, IT or related field OR (experience)
  • Bachelor’s degree with 10 to 14 years of experience Computer Science, IT or related field OR (experience)
  • Diploma with 14 to 18 years of experience Computer Science, IT or related field (experience)
  • Proficiency in designing scalable, secure, and cost-effective solutions (experience)
  • Expertise in cloud platforms (AWS, Azure, GCP), data lakes, and data warehouses (experience)
  • Experience in evaluating and selecting technology vendors (experience)
  • Ability to create and demonstrate proof of concept solutions to validate technical feasibility (experience)
  • Strong knowledge of Clinical Research and Development Domain (experience)
  • Experience working in agile methodology, including Product Teams and Product Development models (experience)

Responsibilities

  • Develop and maintain the enterprise architecture vision and strategy, ensuring alignment with business objectives
  • Create and maintain architectural roadmaps that guide the evolution of IT systems and capabilities
  • Establish and enforce architectural standards, policies, and governance frameworks
  • Evaluate emerging technologies and assess their potential impact on the enterprise/domain/solution architecture
  • Identify and mitigate architectural risks, ensuring that IT systems are scalable, secure, and resilient
  • Maintain comprehensive documentation of the architecture, including principles, standards, and models
  • Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
  • Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
  • Evaluate and recommend technologies and tools that best fit the solution requirements
  • Ensure seamless integration between systems and platforms, both within the organization and with external partners
  • Design systems that can scale to meet growing business needs and performance demands
  • Develop and maintain logical, physical, and conceptual data models to support business needs
  • Establish and enforce data standards, governance policies, and best practices
  • Design and manage metadata structures to enhance information retrieval and usability

Benefits

  • general: Competitive benefits
  • general: Collaborative culture
  • general: Support for professional and personal growth and well-being
  • general: Competitive and comprehensive Total Rewards Plans that are aligned with local industry standards

Target Your Resume for "Principal IS Architect – Clinical Computation Platform" , Amgen

Get personalized recommendations to optimize your resume specifically for Principal IS Architect – Clinical Computation Platform. Takes only 15 seconds!

AI-powered keyword optimization
Skills matching & gap analysis
Experience alignment suggestions

Check Your ATS Score for "Principal IS Architect – Clinical Computation Platform" , Amgen

Find out how well your resume matches this job's requirements. Get comprehensive analysis including ATS compatibility, keyword matching, skill gaps, and personalized recommendations.

ATS compatibility check
Keyword optimization analysis
Skill matching & gap identification
Format & readability score

Tags & Categories

Software EngineeringCloudFull StackInformation SystemsTechnology

Related Jobs You May Like

No related jobs found at the moment.