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Sr Machine Learning Engineer

Amgen

Software and Technology Jobs

Sr Machine Learning Engineer

full-timePosted: Nov 12, 2025

Job Description

ABOUT AMGEN

What you will do

  • Engineer end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimisation, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks.
  • Harden research code into production-grade micro-services, packaging models in Docker/Kubernetes and exposing secure REST, gRPC or event-driven APIs for consumption by downstream applications.
  • Build and maintain full-stack AI applications by integrating model services with lightweight UI components, workflow engines or business-logic layers so insights reach users with sub-second latency.
  • Optimise performance and cost at scale—selecting appropriate algorithms (gradient-boosted trees, transformers, time-series models, classical statistics), applying quantisation/pruning, and tuning GPU/CPU auto-scaling policies to meet strict SLA targets.
  • Instrument comprehensive observability—real-time metrics, distributed tracing, drift & bias detection and user-behaviour analytics—enabling rapid diagnosis and continuous improvement of live models and applications.
  • Embed security and responsible-AI controls (data encryption, access policies, lineage tracking, explainability and bias monitoring) in partnership with Security, Privacy and Compliance teams.
  • Contribute reusable platform components—feature stores, model registries, experiment-tracking libraries—and evangelise best practices that raise engineering velocity across squads.
  • Perform exploratory data analysis and feature ideation on complex, high-dimensional datasets to inform algorithm selection and ensure model robustness.
  • Partner with data scientists to prototype and benchmark new algorithms, offering guidance on scalability trade-offs and production-readiness while co-owning model-performance KPIs.

What we expect of you

  • Master’s degree with 6-11 + years of experience in Computer Science, IT or related field OR Bachelor’s degree with 8-13 + years of experience in Computer Science, IT or related field
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus.
  • 3-5 years in AI/ML and enterprise software.

Must-Have Skills

  • Comprehensive command of machine-learning algorithms—regression, tree-based ensembles, clustering, dimensionality reduction, time-series models, deep-learning architectures (CNNs, RNNs, transformers) and modern LLM/RAG techniques—with the judgment to choose, tune and operationalise the right method for a given business problem.
  • Proven track record selecting and integrating AI SaaS/PaaS offerings and building custom ML services at scale.
  • Expert knowledge of GenAI tooling: vector databases, RAG pipelines, prompt-engineering DSLs and agent frameworks (e.g., LangChain, Semantic Kernel).
  • Proficiency in Python and Java; containerisation (Docker/K8s); cloud (AWS, Azure or GCP) and modern DevOps/MLOps (GitHub Actions, Bedrock/SageMaker Pipelines).
  • Strong business-case skills—able to model TCO vs. NPV and present trade-offs to executives.
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives.
  • Experience in Biotechnology or pharma industry is a big plus
  • Published thought-leadership or conference talks on enterprise GenAI adoption.
  • Master’s degree in Computer Science and or Data Science
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery.
  • Excellent analytical and troubleshooting skills.
  • Strong verbal and written communication skills
  • Ability to work effectively with global, virtual teams
  • High degree of initiative and self-motivation.
  • Ability to manage multiple priorities successfully.
  • Team-oriented, with a focus on achieving team goals.
  • Ability to learn quickly, be organized and detail oriented.
  • Strong presentation and public speaking skills.

Compensation

3-5

Locations

  • Hyderabad, India

Salary

Estimated Salary Rangehigh confidence

80,000 - 120,000 USD / yearly

Source: xAI estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Comprehensive command of machine-learning algorithms—regression, tree-based ensembles, clustering, dimensionality reduction, time-series models, deep-learning architectures (CNNs, RNNs, transformers) and modern LLM/RAG techniques—with the judgment to choose, tune and operationalise the right method for a given business problem.intermediate
  • Proven track record selecting and integrating AI SaaS/PaaS offerings and building custom ML services at scale.intermediate
  • Expert knowledge of GenAI tooling: vector databases, RAG pipelines, prompt-engineering DSLs and agent frameworks (e.g., LangChain, Semantic Kernel).intermediate
  • Proficiency in Python and Java; containerisation (Docker/K8s); cloud (AWS, Azure or GCP) and modern DevOps/MLOps (GitHub Actions, Bedrock/SageMaker Pipelines).intermediate
  • Strong business-case skills—able to model TCO vs. NPV and present trade-offs to executives.intermediate
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives.intermediate
  • Experience in Biotechnology or pharma industry is a big plusintermediate
  • Published thought-leadership or conference talks on enterprise GenAI adoption.intermediate
  • Master’s degree in Computer Science and or Data Scienceintermediate
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery.intermediate
  • Excellent analytical and troubleshooting skills.intermediate
  • Strong verbal and written communication skillsintermediate
  • Ability to work effectively with global, virtual teamsintermediate
  • High degree of initiative and self-motivation.intermediate
  • Ability to manage multiple priorities successfully.intermediate
  • Team-oriented, with a focus on achieving team goals.intermediate
  • Ability to learn quickly, be organized and detail oriented.intermediate
  • Strong presentation and public speaking skills.intermediate

Required Qualifications

  • Master’s degree with 6-11 + years of experience in Computer Science, IT or related field OR Bachelor’s degree with 8-13 + years of experience in Computer Science, IT or related field (experience)
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus. (experience)
  • 3-5 years in AI/ML and enterprise software. (experience)

Responsibilities

  • Engineer end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimisation, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks.
  • Harden research code into production-grade micro-services, packaging models in Docker/Kubernetes and exposing secure REST, gRPC or event-driven APIs for consumption by downstream applications.
  • Build and maintain full-stack AI applications by integrating model services with lightweight UI components, workflow engines or business-logic layers so insights reach users with sub-second latency.
  • Optimise performance and cost at scale—selecting appropriate algorithms (gradient-boosted trees, transformers, time-series models, classical statistics), applying quantisation/pruning, and tuning GPU/CPU auto-scaling policies to meet strict SLA targets.
  • Instrument comprehensive observability—real-time metrics, distributed tracing, drift & bias detection and user-behaviour analytics—enabling rapid diagnosis and continuous improvement of live models and applications.
  • Embed security and responsible-AI controls (data encryption, access policies, lineage tracking, explainability and bias monitoring) in partnership with Security, Privacy and Compliance teams.
  • Contribute reusable platform components—feature stores, model registries, experiment-tracking libraries—and evangelise best practices that raise engineering velocity across squads.
  • Perform exploratory data analysis and feature ideation on complex, high-dimensional datasets to inform algorithm selection and ensure model robustness.
  • Partner with data scientists to prototype and benchmark new algorithms, offering guidance on scalability trade-offs and production-readiness while co-owning model-performance KPIs.

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Amgen logo

Sr Machine Learning Engineer

Amgen

Software and Technology Jobs

Sr Machine Learning Engineer

full-timePosted: Nov 12, 2025

Job Description

ABOUT AMGEN

What you will do

  • Engineer end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimisation, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks.
  • Harden research code into production-grade micro-services, packaging models in Docker/Kubernetes and exposing secure REST, gRPC or event-driven APIs for consumption by downstream applications.
  • Build and maintain full-stack AI applications by integrating model services with lightweight UI components, workflow engines or business-logic layers so insights reach users with sub-second latency.
  • Optimise performance and cost at scale—selecting appropriate algorithms (gradient-boosted trees, transformers, time-series models, classical statistics), applying quantisation/pruning, and tuning GPU/CPU auto-scaling policies to meet strict SLA targets.
  • Instrument comprehensive observability—real-time metrics, distributed tracing, drift & bias detection and user-behaviour analytics—enabling rapid diagnosis and continuous improvement of live models and applications.
  • Embed security and responsible-AI controls (data encryption, access policies, lineage tracking, explainability and bias monitoring) in partnership with Security, Privacy and Compliance teams.
  • Contribute reusable platform components—feature stores, model registries, experiment-tracking libraries—and evangelise best practices that raise engineering velocity across squads.
  • Perform exploratory data analysis and feature ideation on complex, high-dimensional datasets to inform algorithm selection and ensure model robustness.
  • Partner with data scientists to prototype and benchmark new algorithms, offering guidance on scalability trade-offs and production-readiness while co-owning model-performance KPIs.

What we expect of you

  • Master’s degree with 6-11 + years of experience in Computer Science, IT or related field OR Bachelor’s degree with 8-13 + years of experience in Computer Science, IT or related field
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus.
  • 3-5 years in AI/ML and enterprise software.

Must-Have Skills

  • Comprehensive command of machine-learning algorithms—regression, tree-based ensembles, clustering, dimensionality reduction, time-series models, deep-learning architectures (CNNs, RNNs, transformers) and modern LLM/RAG techniques—with the judgment to choose, tune and operationalise the right method for a given business problem.
  • Proven track record selecting and integrating AI SaaS/PaaS offerings and building custom ML services at scale.
  • Expert knowledge of GenAI tooling: vector databases, RAG pipelines, prompt-engineering DSLs and agent frameworks (e.g., LangChain, Semantic Kernel).
  • Proficiency in Python and Java; containerisation (Docker/K8s); cloud (AWS, Azure or GCP) and modern DevOps/MLOps (GitHub Actions, Bedrock/SageMaker Pipelines).
  • Strong business-case skills—able to model TCO vs. NPV and present trade-offs to executives.
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives.
  • Experience in Biotechnology or pharma industry is a big plus
  • Published thought-leadership or conference talks on enterprise GenAI adoption.
  • Master’s degree in Computer Science and or Data Science
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery.
  • Excellent analytical and troubleshooting skills.
  • Strong verbal and written communication skills
  • Ability to work effectively with global, virtual teams
  • High degree of initiative and self-motivation.
  • Ability to manage multiple priorities successfully.
  • Team-oriented, with a focus on achieving team goals.
  • Ability to learn quickly, be organized and detail oriented.
  • Strong presentation and public speaking skills.

Compensation

3-5

Locations

  • Hyderabad, India

Salary

Estimated Salary Rangehigh confidence

80,000 - 120,000 USD / yearly

Source: xAI estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Comprehensive command of machine-learning algorithms—regression, tree-based ensembles, clustering, dimensionality reduction, time-series models, deep-learning architectures (CNNs, RNNs, transformers) and modern LLM/RAG techniques—with the judgment to choose, tune and operationalise the right method for a given business problem.intermediate
  • Proven track record selecting and integrating AI SaaS/PaaS offerings and building custom ML services at scale.intermediate
  • Expert knowledge of GenAI tooling: vector databases, RAG pipelines, prompt-engineering DSLs and agent frameworks (e.g., LangChain, Semantic Kernel).intermediate
  • Proficiency in Python and Java; containerisation (Docker/K8s); cloud (AWS, Azure or GCP) and modern DevOps/MLOps (GitHub Actions, Bedrock/SageMaker Pipelines).intermediate
  • Strong business-case skills—able to model TCO vs. NPV and present trade-offs to executives.intermediate
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives.intermediate
  • Experience in Biotechnology or pharma industry is a big plusintermediate
  • Published thought-leadership or conference talks on enterprise GenAI adoption.intermediate
  • Master’s degree in Computer Science and or Data Scienceintermediate
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery.intermediate
  • Excellent analytical and troubleshooting skills.intermediate
  • Strong verbal and written communication skillsintermediate
  • Ability to work effectively with global, virtual teamsintermediate
  • High degree of initiative and self-motivation.intermediate
  • Ability to manage multiple priorities successfully.intermediate
  • Team-oriented, with a focus on achieving team goals.intermediate
  • Ability to learn quickly, be organized and detail oriented.intermediate
  • Strong presentation and public speaking skills.intermediate

Required Qualifications

  • Master’s degree with 6-11 + years of experience in Computer Science, IT or related field OR Bachelor’s degree with 8-13 + years of experience in Computer Science, IT or related field (experience)
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus. (experience)
  • 3-5 years in AI/ML and enterprise software. (experience)

Responsibilities

  • Engineer end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimisation, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks.
  • Harden research code into production-grade micro-services, packaging models in Docker/Kubernetes and exposing secure REST, gRPC or event-driven APIs for consumption by downstream applications.
  • Build and maintain full-stack AI applications by integrating model services with lightweight UI components, workflow engines or business-logic layers so insights reach users with sub-second latency.
  • Optimise performance and cost at scale—selecting appropriate algorithms (gradient-boosted trees, transformers, time-series models, classical statistics), applying quantisation/pruning, and tuning GPU/CPU auto-scaling policies to meet strict SLA targets.
  • Instrument comprehensive observability—real-time metrics, distributed tracing, drift & bias detection and user-behaviour analytics—enabling rapid diagnosis and continuous improvement of live models and applications.
  • Embed security and responsible-AI controls (data encryption, access policies, lineage tracking, explainability and bias monitoring) in partnership with Security, Privacy and Compliance teams.
  • Contribute reusable platform components—feature stores, model registries, experiment-tracking libraries—and evangelise best practices that raise engineering velocity across squads.
  • Perform exploratory data analysis and feature ideation on complex, high-dimensional datasets to inform algorithm selection and ensure model robustness.
  • Partner with data scientists to prototype and benchmark new algorithms, offering guidance on scalability trade-offs and production-readiness while co-owning model-performance KPIs.

Target Your Resume for "Sr Machine Learning Engineer" , Amgen

Get personalized recommendations to optimize your resume specifically for Sr Machine Learning Engineer. Takes only 15 seconds!

AI-powered keyword optimization
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Experience alignment suggestions

Check Your ATS Score for "Sr Machine Learning Engineer" , Amgen

Find out how well your resume matches this job's requirements. Get comprehensive analysis including ATS compatibility, keyword matching, skill gaps, and personalized recommendations.

ATS compatibility check
Keyword optimization analysis
Skill matching & gap identification
Format & readability score

Tags & Categories

Software EngineeringCloudFull StackInformation SystemsTechnology

Answer 10 quick questions to check your fit for Sr Machine Learning Engineer @ Amgen.

Quiz Challenge
10 Questions
~2 Minutes
Instant Score

Related Books and Jobs

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