Senior Principal Scientist, Discovery Chemistry
Bristol-Myers Squibb
Senior Principal Scientist, Discovery Chemistry
Job Description
Ph.D. in synthetic organic chemistry with 6+ years pharmaceutical medicinal chemistry industrial experience (8+ years preferred) or M.S. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience (10+ years preferred) or B.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience (12+ years preferred) Previous experience supporting and advancing target protein degradation and/or antibody-drug conjugate programs is preferred. Demonstrated ability to contribute and advance drug discovery programs with strong proficiency in fundamental aspects of drug discovery are required Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals is necessary (may include both successful advances and data-driven terminations) Strong working knowledge of protein-ligand interactions, ADME, conformational and structural analysis, experienced in partnering closely with computational chemists through appropriate use of AI/ML and computational predictive tools and models as well as visualization applications. High level of creativity and productivity with strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms are required Ability to champion chemistry efforts into new directions to achieve project milestones Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy Proven leadership capability in cross-functional teams, either as project team leader or co-leader Proven track record of mentoring PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship and focused development activities Excellent communication skills and able to present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Supporting People with Disabilities
About the Role/Company
- The company supports people with disabilities
Key Responsibilities
- Contribute and advance drug discovery programs
- Champion chemistry efforts into new directions to achieve project milestones
- Gather, document, and analyze information from competitive sources such as patents and meetings to guide program strategy
- Lead cross-functional teams, either as project team leader or co-leader
- Mentor PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving their skills and knowledge through mentorship and focused development activities
- Present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization
Required Qualifications
- Ph.D. in synthetic organic chemistry with 6+ years pharmaceutical medicinal chemistry industrial experience
- M.S. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience
- B.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience
- Demonstrated ability to contribute and advance drug discovery programs with strong proficiency in fundamental aspects of drug discovery
- Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals
- High level of creativity and productivity with strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms
- Ability to champion chemistry efforts into new directions to achieve project milestones
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy
- Proven leadership capability in cross-functional teams, either as project team leader or co-leader
- Proven track record of mentoring PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship and focused development activities
- Excellent communication skills and able to present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization
Preferred Qualifications
- Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience
- M.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience
- B.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience
- Previous experience supporting and advancing target protein degradation and/or antibody-drug conjugate programs
Skills Required
- Strong proficiency in fundamental aspects of drug discovery
- Strong working knowledge of protein-ligand interactions, ADME, conformational and structural analysis
- Experienced in partnering closely with computational chemists through appropriate use of AI/ML and computational predictive tools and models as well as visualization applications
- High level of creativity and productivity
- Strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms
- Strong skills in gathering, documenting, and analyzing information from competitive sources
- Proven leadership capability
- Excellent communication skills
Benefits & Perks
- Paid national holidays and optional holidays
- Global Shutdown Days between Christmas and New Year's holiday
- Up to 120 hours of paid vacation
- Up to two (2) paid days to volunteer
- Sick time off
- Summer hours flexibility
Locations
- San Diego CA, United States
Salary
Salary not disclosed
Estimated Salary Rangemedium confidence
180,000 - 250,000 USD / yearly
Source: ai estimated
* This is an estimated range based on market data and may vary based on experience and qualifications.
Skills Required
- Strong proficiency in fundamental aspects of drug discoveryintermediate
- Strong working knowledge of protein-ligand interactions, ADME, conformational and structural analysisintermediate
- Experienced in partnering closely with computational chemists through appropriate use of AI/ML and computational predictive tools and models as well as visualization applicationsintermediate
- High level of creativity and productivityintermediate
- Strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanismsintermediate
- Strong skills in gathering, documenting, and analyzing information from competitive sourcesintermediate
- Proven leadership capabilityintermediate
- Excellent communication skillsintermediate
Required Qualifications
- Ph.D. in synthetic organic chemistry with 6+ years pharmaceutical medicinal chemistry industrial experience (experience)
- M.S. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience (experience)
- B.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience (experience)
- Demonstrated ability to contribute and advance drug discovery programs with strong proficiency in fundamental aspects of drug discovery (experience)
- Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals (experience)
- High level of creativity and productivity with strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms (experience)
- Ability to champion chemistry efforts into new directions to achieve project milestones (experience)
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy (experience)
- Proven leadership capability in cross-functional teams, either as project team leader or co-leader (experience)
- Proven track record of mentoring PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship and focused development activities (experience)
- Excellent communication skills and able to present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization (experience)
Preferred Qualifications
- Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience (experience)
- M.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience (experience)
- B.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience (experience)
- Previous experience supporting and advancing target protein degradation and/or antibody-drug conjugate programs (experience)
Responsibilities
- Contribute and advance drug discovery programs
- Champion chemistry efforts into new directions to achieve project milestones
- Gather, document, and analyze information from competitive sources such as patents and meetings to guide program strategy
- Lead cross-functional teams, either as project team leader or co-leader
- Mentor PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving their skills and knowledge through mentorship and focused development activities
- Present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization
Benefits
- general: Paid national holidays and optional holidays
- general: Global Shutdown Days between Christmas and New Year's holiday
- general: Up to 120 hours of paid vacation
- general: Up to two (2) paid days to volunteer
- general: Sick time off
- general: Summer hours flexibility
Tags & Categories
Senior Principal Scientist, Discovery Chemistry
Bristol-Myers Squibb
Senior Principal Scientist, Discovery Chemistry
Job Description
Ph.D. in synthetic organic chemistry with 6+ years pharmaceutical medicinal chemistry industrial experience (8+ years preferred) or M.S. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience (10+ years preferred) or B.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience (12+ years preferred) Previous experience supporting and advancing target protein degradation and/or antibody-drug conjugate programs is preferred. Demonstrated ability to contribute and advance drug discovery programs with strong proficiency in fundamental aspects of drug discovery are required Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals is necessary (may include both successful advances and data-driven terminations) Strong working knowledge of protein-ligand interactions, ADME, conformational and structural analysis, experienced in partnering closely with computational chemists through appropriate use of AI/ML and computational predictive tools and models as well as visualization applications. High level of creativity and productivity with strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms are required Ability to champion chemistry efforts into new directions to achieve project milestones Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy Proven leadership capability in cross-functional teams, either as project team leader or co-leader Proven track record of mentoring PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship and focused development activities Excellent communication skills and able to present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Supporting People with Disabilities
About the Role/Company
- The company supports people with disabilities
Key Responsibilities
- Contribute and advance drug discovery programs
- Champion chemistry efforts into new directions to achieve project milestones
- Gather, document, and analyze information from competitive sources such as patents and meetings to guide program strategy
- Lead cross-functional teams, either as project team leader or co-leader
- Mentor PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving their skills and knowledge through mentorship and focused development activities
- Present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization
Required Qualifications
- Ph.D. in synthetic organic chemistry with 6+ years pharmaceutical medicinal chemistry industrial experience
- M.S. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience
- B.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience
- Demonstrated ability to contribute and advance drug discovery programs with strong proficiency in fundamental aspects of drug discovery
- Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals
- High level of creativity and productivity with strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms
- Ability to champion chemistry efforts into new directions to achieve project milestones
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy
- Proven leadership capability in cross-functional teams, either as project team leader or co-leader
- Proven track record of mentoring PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship and focused development activities
- Excellent communication skills and able to present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization
Preferred Qualifications
- Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience
- M.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience
- B.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience
- Previous experience supporting and advancing target protein degradation and/or antibody-drug conjugate programs
Skills Required
- Strong proficiency in fundamental aspects of drug discovery
- Strong working knowledge of protein-ligand interactions, ADME, conformational and structural analysis
- Experienced in partnering closely with computational chemists through appropriate use of AI/ML and computational predictive tools and models as well as visualization applications
- High level of creativity and productivity
- Strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms
- Strong skills in gathering, documenting, and analyzing information from competitive sources
- Proven leadership capability
- Excellent communication skills
Benefits & Perks
- Paid national holidays and optional holidays
- Global Shutdown Days between Christmas and New Year's holiday
- Up to 120 hours of paid vacation
- Up to two (2) paid days to volunteer
- Sick time off
- Summer hours flexibility
Locations
- San Diego CA, United States
Salary
Salary not disclosed
Estimated Salary Rangemedium confidence
180,000 - 250,000 USD / yearly
Source: ai estimated
* This is an estimated range based on market data and may vary based on experience and qualifications.
Skills Required
- Strong proficiency in fundamental aspects of drug discoveryintermediate
- Strong working knowledge of protein-ligand interactions, ADME, conformational and structural analysisintermediate
- Experienced in partnering closely with computational chemists through appropriate use of AI/ML and computational predictive tools and models as well as visualization applicationsintermediate
- High level of creativity and productivityintermediate
- Strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanismsintermediate
- Strong skills in gathering, documenting, and analyzing information from competitive sourcesintermediate
- Proven leadership capabilityintermediate
- Excellent communication skillsintermediate
Required Qualifications
- Ph.D. in synthetic organic chemistry with 6+ years pharmaceutical medicinal chemistry industrial experience (experience)
- M.S. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience (experience)
- B.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience (experience)
- Demonstrated ability to contribute and advance drug discovery programs with strong proficiency in fundamental aspects of drug discovery (experience)
- Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals (experience)
- High level of creativity and productivity with strong synthetic productivity, problem solving skills, synthetic methods, and reaction mechanisms (experience)
- Ability to champion chemistry efforts into new directions to achieve project milestones (experience)
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy (experience)
- Proven leadership capability in cross-functional teams, either as project team leader or co-leader (experience)
- Proven track record of mentoring PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship and focused development activities (experience)
- Excellent communication skills and able to present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization (experience)
Preferred Qualifications
- Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience (experience)
- M.S. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience (experience)
- B.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience (experience)
- Previous experience supporting and advancing target protein degradation and/or antibody-drug conjugate programs (experience)
Responsibilities
- Contribute and advance drug discovery programs
- Champion chemistry efforts into new directions to achieve project milestones
- Gather, document, and analyze information from competitive sources such as patents and meetings to guide program strategy
- Lead cross-functional teams, either as project team leader or co-leader
- Mentor PhD and/or MSc/BSc-level scientists to high levels of productivity, whilst improving their skills and knowledge through mentorship and focused development activities
- Present the rationale, key data, issues and accomplishments of the chemistry efforts to other members of the R&ED organization
Benefits
- general: Paid national holidays and optional holidays
- general: Global Shutdown Days between Christmas and New Year's holiday
- general: Up to 120 hours of paid vacation
- general: Up to two (2) paid days to volunteer
- general: Sick time off
- general: Summer hours flexibility
Tags & Categories