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Senior Scientist, Immuno-Oncology, Discovery Biology

Bristol-Myers Squibb

Healthcare Jobs

Senior Scientist, Immuno-Oncology, Discovery Biology

full-timePosted: Oct 15, 2025

Job Description

In the role as a Senior Scientist within Discovery Biology, the ideal candidate will: Identify and validate novel targets for development of T cell engagers. Independently design, develop and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers. Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles. Design and implement critical studies required to drive hypothesis-driven research. Collaborate across multiple projects / roles in a matrixed environment. Present complex concepts to a range of audiences including governance and full team project meetings. Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Bachelor's Degree 6+ years of relevant academic and / or industry experience Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field 2+ years of relevant academic and / or industry experience Knowledge of T cell biology and relevant in vitro assay systems and experience with transformed tumor cells is strongly preferred. Experience with technologies typically employed to engineer cell lines and assess immune cell function including but not limited to subset of CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies. Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation Self-motivated and focused with project management-oriented thinking; able to work on multiple projects in a matrix environment Ability to communicate well with peers, supervisors, and governance committees. Strong problem-solving skills and understanding of complex scientific principles. Requires strong organizational skills to ensure thorough and timely documentation of experiments, and preparation of data for compiling reports for both internal and external documents. Experience with antibody drug discovery and target identification / validation is an advantage.

Key Responsibilities

  • Identify and validate novel targets for development of T cell engagers
  • Independently design, develop, and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers
  • Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles
  • Design and implement critical studies required to drive hypothesis-driven research
  • Collaborate across multiple projects/roles in a matrixed environment
  • Present complex concepts to a range of audiences including governance and full team project meetings
  • Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders

Required Qualifications

  • Bachelor's Degree with 6+ years of relevant academic and/or industry experience
  • Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience

Preferred Qualifications

  • Knowledge of T cell biology and relevant in vitro assay systems
  • Experience with transformed tumor cells
  • Experience with technologies such as CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies
  • Experience with antibody drug discovery and target identification/validation

Skills Required

  • Excellent communication and interpersonal skills
  • Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation
  • Self-motivated and focused with project management-oriented thinking
  • Ability to work on multiple projects in a matrix environment
  • Strong problem-solving skills and understanding of complex scientific principles
  • Strong organizational skills for thorough and timely documentation of experiments and preparation of data for reports

Benefits & Perks

  • Paid national holidays and optional holidays
  • Global Shutdown Days between Christmas and New Year's holiday
  • Up to 120 hours of paid vacation
  • Up to two (2) paid days to volunteer
  • Sick time off
  • Summer hours flexibility

Locations

  • Seattle 400 Dexter WA, United States

Salary

Estimated Salary Rangemedium confidence

150,000 - 220,000 USD / yearly

Source: ai estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Excellent communication and interpersonal skillsintermediate
  • Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentationintermediate
  • Self-motivated and focused with project management-oriented thinkingintermediate
  • Ability to work on multiple projects in a matrix environmentintermediate
  • Strong problem-solving skills and understanding of complex scientific principlesintermediate
  • Strong organizational skills for thorough and timely documentation of experiments and preparation of data for reportsintermediate

Required Qualifications

  • Bachelor's Degree with 6+ years of relevant academic and/or industry experience (experience)
  • Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience (experience)

Preferred Qualifications

  • Knowledge of T cell biology and relevant in vitro assay systems (experience)
  • Experience with transformed tumor cells (experience)
  • Experience with technologies such as CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies (experience)
  • Experience with antibody drug discovery and target identification/validation (experience)

Responsibilities

  • Identify and validate novel targets for development of T cell engagers
  • Independently design, develop, and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers
  • Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles
  • Design and implement critical studies required to drive hypothesis-driven research
  • Collaborate across multiple projects/roles in a matrixed environment
  • Present complex concepts to a range of audiences including governance and full team project meetings
  • Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders

Benefits

  • general: Paid national holidays and optional holidays
  • general: Global Shutdown Days between Christmas and New Year's holiday
  • general: Up to 120 hours of paid vacation
  • general: Up to two (2) paid days to volunteer
  • general: Sick time off
  • general: Summer hours flexibility

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Bristol-Myers Squibb logo

Senior Scientist, Immuno-Oncology, Discovery Biology

Bristol-Myers Squibb

Healthcare Jobs

Senior Scientist, Immuno-Oncology, Discovery Biology

full-timePosted: Oct 15, 2025

Job Description

In the role as a Senior Scientist within Discovery Biology, the ideal candidate will: Identify and validate novel targets for development of T cell engagers. Independently design, develop and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers. Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles. Design and implement critical studies required to drive hypothesis-driven research. Collaborate across multiple projects / roles in a matrixed environment. Present complex concepts to a range of audiences including governance and full team project meetings. Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Bachelor's Degree 6+ years of relevant academic and / or industry experience Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field 2+ years of relevant academic and / or industry experience Knowledge of T cell biology and relevant in vitro assay systems and experience with transformed tumor cells is strongly preferred. Experience with technologies typically employed to engineer cell lines and assess immune cell function including but not limited to subset of CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies. Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation Self-motivated and focused with project management-oriented thinking; able to work on multiple projects in a matrix environment Ability to communicate well with peers, supervisors, and governance committees. Strong problem-solving skills and understanding of complex scientific principles. Requires strong organizational skills to ensure thorough and timely documentation of experiments, and preparation of data for compiling reports for both internal and external documents. Experience with antibody drug discovery and target identification / validation is an advantage.

Key Responsibilities

  • Identify and validate novel targets for development of T cell engagers
  • Independently design, develop, and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers
  • Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles
  • Design and implement critical studies required to drive hypothesis-driven research
  • Collaborate across multiple projects/roles in a matrixed environment
  • Present complex concepts to a range of audiences including governance and full team project meetings
  • Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders

Required Qualifications

  • Bachelor's Degree with 6+ years of relevant academic and/or industry experience
  • Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience

Preferred Qualifications

  • Knowledge of T cell biology and relevant in vitro assay systems
  • Experience with transformed tumor cells
  • Experience with technologies such as CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies
  • Experience with antibody drug discovery and target identification/validation

Skills Required

  • Excellent communication and interpersonal skills
  • Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation
  • Self-motivated and focused with project management-oriented thinking
  • Ability to work on multiple projects in a matrix environment
  • Strong problem-solving skills and understanding of complex scientific principles
  • Strong organizational skills for thorough and timely documentation of experiments and preparation of data for reports

Benefits & Perks

  • Paid national holidays and optional holidays
  • Global Shutdown Days between Christmas and New Year's holiday
  • Up to 120 hours of paid vacation
  • Up to two (2) paid days to volunteer
  • Sick time off
  • Summer hours flexibility

Locations

  • Seattle 400 Dexter WA, United States

Salary

Estimated Salary Rangemedium confidence

150,000 - 220,000 USD / yearly

Source: ai estimated

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • Excellent communication and interpersonal skillsintermediate
  • Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentationintermediate
  • Self-motivated and focused with project management-oriented thinkingintermediate
  • Ability to work on multiple projects in a matrix environmentintermediate
  • Strong problem-solving skills and understanding of complex scientific principlesintermediate
  • Strong organizational skills for thorough and timely documentation of experiments and preparation of data for reportsintermediate

Required Qualifications

  • Bachelor's Degree with 6+ years of relevant academic and/or industry experience (experience)
  • Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience (experience)

Preferred Qualifications

  • Knowledge of T cell biology and relevant in vitro assay systems (experience)
  • Experience with transformed tumor cells (experience)
  • Experience with technologies such as CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies (experience)
  • Experience with antibody drug discovery and target identification/validation (experience)

Responsibilities

  • Identify and validate novel targets for development of T cell engagers
  • Independently design, develop, and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers
  • Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles
  • Design and implement critical studies required to drive hypothesis-driven research
  • Collaborate across multiple projects/roles in a matrixed environment
  • Present complex concepts to a range of audiences including governance and full team project meetings
  • Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders

Benefits

  • general: Paid national holidays and optional holidays
  • general: Global Shutdown Days between Christmas and New Year's holiday
  • general: Up to 120 hours of paid vacation
  • general: Up to two (2) paid days to volunteer
  • general: Sick time off
  • general: Summer hours flexibility

Target Your Resume for "Senior Scientist, Immuno-Oncology, Discovery Biology" , Bristol-Myers Squibb

Get personalized recommendations to optimize your resume specifically for Senior Scientist, Immuno-Oncology, Discovery Biology. Takes only 15 seconds!

AI-powered keyword optimization
Skills matching & gap analysis
Experience alignment suggestions

Check Your ATS Score for "Senior Scientist, Immuno-Oncology, Discovery Biology" , Bristol-Myers Squibb

Find out how well your resume matches this job's requirements. Get comprehensive analysis including ATS compatibility, keyword matching, skill gaps, and personalized recommendations.

ATS compatibility check
Keyword optimization analysis
Skill matching & gap identification
Format & readability score

Tags & Categories

PharmaceuticalPharmaceuticalHealthcare

Answer 10 quick questions to check your fit for Senior Scientist, Immuno-Oncology, Discovery Biology @ Bristol-Myers Squibb.

Quiz Challenge
10 Questions
~2 Minutes
Instant Score

Related Books and Jobs

No related jobs found at the moment.