About Gilead Sciences

Gilead Sciences is a leading biopharmaceutical company headquartered in Foster City, California, dedicated to creating a healthier world for all. For over 35 years, Gilead has pioneered breakthroughs in treating HIV, viral hepatitis, COVID-19, cancer, and inflammatory diseases. Our innovative therapies have transformed lives globally, from life-saving HIV treatments like Biktarvy to cutting-edge oncology drugs and antivirals combating viral hepatitis. In oncology, Gilead advances targeted therapies for hard-to-treat cancers, while in inflammation, we develop solutions for autoimmune conditions. Our virology portfolio continues to set standards in HIV and hepatitis care. With a relentless drive for scientific innovation, Gilead collaborates across therapeutic areas to ensure accessible therapies worldwide.

Role Overview

The Director, Pharmacometrics position at Gilead Sciences in Foster City, California, is a pivotal leadership role within our clinical pharmacology team. You will spearhead quantitative analyses across Oncology, Inflammation, and Virology therapeutic areas, guiding drug development from first-in-human trials through Phase IV. This role demands expertise in model-informed drug development (MIDD), regulatory strategy, and cross-functional collaboration. As a subject matter expert, you'll influence data-driven decisions, optimize dosing regimens, and support global filings like INDs, NDAs, and BLAs. Join a team that's at the forefront of biopharma innovation, leveraging state-of-the-art pharmacometrics to accelerate life-changing therapies.

Key Responsibilities

In this director-level position, your impact will span the entire drug lifecycle:

• Lead innovative quantitative strategies in clinical pharmacology to advance MIDD across programs.
• Evaluate and apply advanced pharmacometrics approaches for decision-making and regulatory submissions.
• Develop high-quality modeling and simulation plans, author reports, and present findings to regulators and stakeholders.
• Guide dose optimization in partnership with therapeutic area leads.
• Ensure deliverables meet timelines and budgets, while providing training on pharmacometrics best practices.

Strategic Leadership

You'll champion MIDD, interpreting complex analyses to drive program success in oncology, inflammation, and virology—key pillars of Gilead's portfolio.

Qualifications & Requirements

To excel as Director, Pharmacometrics, candidates must meet these rigorous standards:

• PhD (or equivalent) in engineering, pharmaceutical sciences, pharmacology, or related field with 8+ years of relevant pharmacometrics experience.
• Master’s with 10+ years or Bachelor’s with 12+ years of experience.
• Extensive experience leading cross-functional teams and authoring modeling/simulation plans for Phases I-IV.
• Proficiency in mathematics, quantitative analyses, and therapeutic knowledge in oncology, virology, or inflammation.
• Strong communication skills to engage executives, regulators, and teams; flexibility, adaptability, and travel readiness as needed.

Preferred Expertise

Ideal candidates bring sustained scientific excellence, matrix management prowess, and deep physiological/pharmacological insights.

Benefits & Perks

Gilead offers a premium compensation package for this role:

• Salary range: $226,185 - $292,710 USD, based on experience and location.
• Discretionary annual bonus and stock-based long-term incentives.
• Comprehensive benefits including medical, dental, vision, and life insurance.
• Paid time off, wellness programs, and family support.
• Access to cutting-edge resources in Foster City’s biotech hub.

Career Growth

At Gilead, people leaders drive culture and employee empowerment. This role positions you for executive advancement in pharmacometrics and clinical development. Benefit from mentorship, training, and cross-therapeutic exposure in HIV, oncology, and inflammation. Gilead’s commitment to inclusion fosters rapid career progression for ambitious experts.

Why Join Gilead

Gilead is more than a biopharma leader—we’re a mission-driven force against global health challenges. Work on groundbreaking therapies in HIV (e.g., reducing viral loads to undetectable levels), oncology (targeted cancer treatments), and inflammatory diseases (novel immunomodulators). In Foster City, collaborate with top scientists in a collaborative, innovative environment. Your pharmacometrics expertise will directly impact patients worldwide, supported by robust resources and a culture of excellence.

Role FAQs

What therapeutic areas does this role cover?

Oncology, Inflammation, and Virology—core to Gilead’s portfolio.

Is travel required?

Occasional travel as needed for collaborations and meetings.

What is the salary range?

$226,185 - $292,710 USD, plus bonuses and equity.

Are there leadership opportunities?

Yes, as a people leader, you’ll shape teams and culture.

How does Gilead support professional development?

Through training, cross-functional projects, and executive exposure.