About Gilead Sciences

Gilead Sciences is a leading biopharmaceutical company headquartered in Foster City, California, with over 35 years of dedication to creating a healthier world. Renowned for groundbreaking therapies in HIV, viral hepatitis, COVID-19, and cancer, Gilead continues to pioneer treatments for oncology and inflammatory diseases. Our mission-driven approach emphasizes collaboration, innovation, and global access to life-changing medicines. As a key player in the biotech industry, Gilead fosters a culture of integrity, inclusion, teamwork, excellence, and accountability, empowering employees to make direct impacts on global health challenges.

Role Overview

The Scientist, Analytical Ops position in Gilead's Pre-Pivotal Biologics Analytical Development group offers a pivotal role in advancing biologic molecules from toxicology through Phase I/II clinical trials. Based in Foster City, California, this full-time role positions you as the analytical lead on Pharmaceutical Development & Manufacturing (PDM) project teams. Leverage state-of-the-art mass spectrometry technologies like Native LC-MS, CE-MS, and high-throughput LC-MS/MS to drive innovation. This opportunity is ideal for analytical chemists passionate about biologics characterization, regulatory compliance, and cross-functional collaboration in a fast-paced, resource-rich environment.

Key Impact Areas

Contribute to Gilead's bold ambitions by identifying critical quality attributes, developing control strategies, and authoring IND filings. Your work directly supports the discovery and development of therapies tackling HIV, oncology, and inflammatory diseases, ensuring seamless progression into clinical stages.

Key Responsibilities

As Scientist, Analytical Ops, you will:

• Lead analytical characterization for pre-pivotal biologic molecules, proposing control strategies and authoring regulatory filings.
• Develop advanced extended characterization methods using mass spectrometry technologies including Native LC-MS, CE-MS, MD-LC-MS, and automated LC-MS/MS.
• Create analytical methods for characterization and release testing with tools like HPLC-UV, CE, iCIEF, and HPLC-CAD, including reports, protocols, and validations.
• Evaluate and implement cutting-edge technologies to innovate in Analytical Development.
• Oversee data generation, integrity, and compliance at internal labs and contract organizations.
• Build relationships with Research, Clinical Development, and Program Strategy teams, providing technical input.
• Support cGMP manufacturing and present findings to senior staff for INDs and patents.

Qualifications & Requirements

To excel in this role, candidates need:

• Ph.D. with 3+ years or M.S. with 6+ years of industrial experience in Analytical Chemistry or related fields focused on biologics.
• Advanced hands-on expertise in LC-MS-based biologics characterization and data analysis for CMC development.
• Proficiency in analytical method development, validation, and control strategies using HPLC, CE-SDS, iCIEF, LC-MS/MS, and more.
• Familiarity with FDA and ICH guidelines for drug substance/product quality and compliance.
• Strong collaboration skills across CMC functions, plus knowledge of lab automation, data governance, and data science.
• Commitment to Gilead's core values: Integrity, Inclusion, Teamwork, Excellence, and Accountability.

Preferred Experience

Hands-on experience with intact/reduced/sub-unit mass analysis, gel electrophoresis, and working in multidisciplinary teams accelerates success.

Benefits & Perks

Gilead Sciences offers a premium compensation package for the Scientist, Analytical Ops role, with a salary range of $146,540 to $189,640, determined by experience, qualifications, and location. Additional perks include:

• Discretionary annual bonus and stock-based long-term incentives.
• Comprehensive health, dental, and vision insurance.
• 401(k) matching, paid time off, and family leave.
• Professional development programs and tuition reimbursement.
• On-site fitness centers, wellness programs, and employee assistance resources.

Enjoy a supportive work environment emphasizing work-life balance and employee well-being.

Career Growth

Gilead invests in your professional journey, offering opportunities to acquire new skills, build networks, and advance into leadership roles. As a people leader or aspiring one, you'll drive cultural evolution, fostering inclusion and empowerment. The Pre-Pivotal Biologics team provides exposure to innovative technologies and high-impact projects, positioning you for growth in analytical development, regulatory affairs, or program management.

Why Join Gilead

Joining Gilead means contributing to therapies that transform lives in HIV, oncology, and inflammatory diseases. Our collaborative culture, state-of-the-art facilities in Foster City, and commitment to diversity make us an employer of choice. Be part of a team relentlessly pursuing scientific innovations, with resources to achieve bold ambitions. Every role at Gilead plays a critical part in our mission—yours can too.

Role FAQs

Q: What is the experience level required?
A: Ph.D. +3 years or M.S. +6 years in biologics analytical development.

Q: Is relocation assistance provided?
A: Gilead offers competitive relocation support for qualifying candidates.

Q: What technologies will I work with?
A: Advanced LC-MS platforms, HPLC, CE, and automation tools for biologics.

Q: How does this role support clinical advancement?
A: By leading analytical strategies for toxicology and Phase I/II biologics.

Q: What are Gilead's core values?
A: Integrity, Inclusion, Teamwork, Excellence, Accountability.