About Gilead Sciences

Gilead Sciences is a leading biopharmaceutical company dedicated to creating a healthier world for all people. For over 35 years, Gilead has pioneered breakthroughs in treating HIV, viral hepatitis, COVID-19, cancer, and inflammatory diseases. Our innovative therapies have transformed lives, ensuring access to life-changing treatments worldwide. Headquartered in Foster City, California, Gilead employs thousands of passionate professionals united by a mission to advance scientific discovery and address global health challenges. As a Sr Director, IT (Manufacturing and Operational Technology Digital Leader), you'll join a dynamic team driving the future of biopharma manufacturing.

Role Overview

The Sr Director, IT (Manufacturing and Operational Technology Digital Leader) role at Gilead Sciences in Foster City, California, is a strategic leadership position reporting to the Head of PDM IT with a dotted line to the Head of Foster City Manufacturing. This site-based role at our Global Headquarters oversees IT, OT, data, and digital strategies for API, OSD GMP facilities, and a new state-of-the-art Single-Use DS Biologics Manufacturing facility. You'll collaborate with local and global partners to implement world-class digital manufacturing technologies, including AI, MES, and process automation, advancing Gilead's digital ambitions in HIV therapies, oncology, and inflammatory disease treatments.

Strategic Impact

As a standing member of the Foster City Site Manufacturing Leadership Team, you'll shape site culture, priorities, and processes while championing AI-driven innovation for operational excellence.

Key Responsibilities

In this pivotal role, you'll deliver transformative leadership across manufacturing IT and OT:

• Develop and execute a comprehensive digital strategy for Foster City Manufacturing, aligned with Gilead's global IT and manufacturing vision.
• Lead the design and implementation of a new Single-Use DS Biologics Manufacturing facility, integrating cutting-edge IT/OT solutions.
• Champion AI-powered tools for predictive maintenance, anomaly detection, process optimization, and real-time insights via IoT and digital twins.
• Shape MES strategy, including platform selection, lifecycle management, and seamless integration with LIMS, PCS, Historian, and enterprise systems.
• Establish secure IT/OT connectivity frameworks, ensuring cybersecurity, GMP compliance, data integrity, and ethical AI governance.
• Represent Foster City Manufacturing in quality investigations, health authority inspections, audits, and regulatory dossiers.
• Foster a culture of continuous learning and AI fluency, sponsoring cross-functional initiatives across the site and manufacturing network.

Qualifications & Requirements

Gilead seeks an exceptional leader with deep expertise in biopharma manufacturing IT/OT:

• Bachelor's or Master's degree in Computer Science, Engineering, or related field; advanced degree preferred.
• 15+ years of progressive experience in IT/OT leadership, with 10+ years in biopharmaceutical manufacturing.
• Proven track record implementing AI/ML for manufacturing optimization, predictive maintenance, and digital twins.
• Hands-on experience with MES, LIMS, PCS, e-Validation, and GMP/non-GMP reporting systems.
• Strong understanding of regulatory standards (GMP, data integrity, cybersecurity) and health authority interactions.
• Excellent leadership skills, with experience influencing site leadership teams and global stakeholders.
• Passionate about emerging technologies like AI trends and their operational impact.

Benefits & Perks

Gilead Sciences offers a premium compensation package tailored for top talent:

• Competitive base salary estimated at $350,000 - $450,000 annually, plus performance bonuses and equity.
• Comprehensive health benefits including medical, dental, vision, and wellness programs.
• Generous 401(k) matching, retirement savings, and financial planning support.
• Paid time off, family leave, and flexible work options where applicable.
• Professional development opportunities, tuition reimbursement, and leadership training.
• Access to on-site amenities at Foster City headquarters, fostering collaboration and innovation.

Career Growth

At Gilead, people leaders are central to our culture of inclusion and empowerment. This Sr Director role offers visibility to executive leadership, with opportunities to influence global manufacturing strategies. Advance your career by leading high-impact digital transformations, mentoring teams, and contributing to Gilead's pipeline in HIV, oncology, and inflammatory diseases. Our commitment to employee development ensures you'll have resources for continuous growth in AI, digital technologies, and biopharma leadership.

Why Join Gilead

Join Gilead to make a direct impact on life-changing therapies. Be part of a collaborative environment where your expertise in manufacturing IT/OT and digital innovation drives operational excellence. Work on groundbreaking projects like the new biologics facility, leveraging AI to minimize downtime, boost OEE, and accelerate product introductions. At our Foster City headquarters, enjoy a supportive culture focused on bold ambitions and employee aspirations, all while advancing treatments for HIV, cancer, viral hepatitis, and inflammatory diseases.

Role FAQs

Q: Is this a hybrid or fully on-site role?
A: This is a site-based role in Foster City, CA, to ensure close collaboration with manufacturing operations.

Q: What technologies will I work with?
A: Key focus on AI/ML, MES, IoT, digital twins, LIMS, PCS, and secure IT/OT integrations.

Q: How does this role support Gilead's mission?
A: By digitalizing manufacturing, you'll enhance efficiency for therapies in HIV, oncology, and inflammatory diseases.

Q: What salary can I expect?
A: Estimated $350,000 - $450,000 USD yearly, based on biopharma sector rates with upside buffer.

Q: Are there leadership development opportunities?
A: Yes, as a Site Leadership Team member, you'll drive culture and cross-functional initiatives.