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Sr Manager, Systems Design Engineering

Thermo Fisher Scientific

Engineering Jobs

Sr Manager, Systems Design Engineering

full-timePosted: Jan 12, 2026

Job Description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Senior Manager, Systems Engineering – qPCR Platforms 

About the Role 

In the role of Systems Engineering Senior Lead, you’ll be the architect and technical owner of our next-generation qPCR systems. You’ll bring together hardware, software, assays, algorithms, and consumables into one cohesive platform — driving innovation from concept to commercialization!

This role blends strategic leadership with hands-on technical depth. You’ll lead a team of architects and engineers, partner with business and product leaders, and ensure every system we build is reliable, scalable, and ground-breaking for our customers. 

 

What You’ll Do 

Own the System Architecture 

  • Define and own the system architecture for integrated qPCR platforms spanning hardware, software, assay, and algorithm development. 

  • Translate user needs and business goals into clear system requirements that balance performance, usability, manufacturability, and compliance. 

  • Lead design trade-offs and technical risk analyses to ensure robustness and scalability. 

  • Champion the architectural vision from early concept through final commercial product. 

Lead multi-functional Integration 

  • Partner closely with Product Management, Operations, Assay, Software, and Algorithm teams to align technology and product strategies. 

  • Drive system-level integration, ensuring seamless collaboration across fields and geographies. 

  • Communicate complex technical decisions and trade-offs to senior collaborators with clarity and influence. 

  • Work hand-in-hand with Manufacturing, Quality, and Service teams to ensure design choices enable smooth scale-up and long-term reliability. 

Drive Innovation and Execution 

  • Serve as the hands-on technical authority for system definition, integration, and root-cause analysis. 
  • Guide technology down-selection, system verification, and early-stage prototyping efforts. 
  • Advance systems engineering practices — adopting model-based methods, simulation tools, and data-driven approaches. 
  • Champion new technologies and ideas that push the boundaries of what’s possible in qPCR instrumentation. 

Build and Develop the Team 

  • Recruit, mentor, and empower an extraordinary systems engineering team. 

  • Create a culture that values innovation, rigor, and collaborative problem-solving. 

  • Provide mentorship and growth opportunities for emerging technical leaders. 

  • Shape and scale systems engineering excellence across the broader R&D organization. 

 

What You Bring 

  • 8+ years of experience in systems engineering or multi-functional product development for life science or diagnostic instruments. 

  • Proven record of leading system integration across hardware, software, and consumables — from concept to launch. 

  • Demonstrated success managing and developing successful technical teams. 

  • Strong experience working in regulated environments (ISO 13485, FDA QSR, CE-IVD). 

  • Ability to partner strategically with Product Management and business leaders to translate vision into executable roadmaps. 

  • Deep understanding of systems engineering principles and broad technical fluency across mechanical, electrical, software, and assay domains. 

  • Excellent communication and influencing skills; comfortable communicating complex ideas to both engineers and executives. 

 

Education 

  • Bachelor’s, Master’s, or Ph.D. in Engineering (Mechanical, Electrical, Systems, or Software) or Applied Physics; advanced degree preferred. 

Locations

  • Singapore, Singapore

Salary

Estimated Salary Rangemedium confidence

90,000 - 150,000 USD / yearly

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • system architectureintermediate
  • systems engineeringintermediate
  • model-based methodsintermediate
  • simulation toolsintermediate
  • data-driven approachesintermediate
  • multi-functional integrationintermediate

Required Qualifications

  • 8+ years experience in systems engineering or multi-functional product development (experience)

Responsibilities

  • Define and own system architecture
  • Translate user needs into requirements
  • Lead design trade-offs and risk analyses
  • Drive system-level integration
  • Mentor and build systems engineering team
  • Guide technology down-selection and prototyping

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Thermo Fisher Scientific logo

Sr Manager, Systems Design Engineering

Thermo Fisher Scientific

Engineering Jobs

Sr Manager, Systems Design Engineering

full-timePosted: Jan 12, 2026

Job Description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Senior Manager, Systems Engineering – qPCR Platforms 

About the Role 

In the role of Systems Engineering Senior Lead, you’ll be the architect and technical owner of our next-generation qPCR systems. You’ll bring together hardware, software, assays, algorithms, and consumables into one cohesive platform — driving innovation from concept to commercialization!

This role blends strategic leadership with hands-on technical depth. You’ll lead a team of architects and engineers, partner with business and product leaders, and ensure every system we build is reliable, scalable, and ground-breaking for our customers. 

 

What You’ll Do 

Own the System Architecture 

  • Define and own the system architecture for integrated qPCR platforms spanning hardware, software, assay, and algorithm development. 

  • Translate user needs and business goals into clear system requirements that balance performance, usability, manufacturability, and compliance. 

  • Lead design trade-offs and technical risk analyses to ensure robustness and scalability. 

  • Champion the architectural vision from early concept through final commercial product. 

Lead multi-functional Integration 

  • Partner closely with Product Management, Operations, Assay, Software, and Algorithm teams to align technology and product strategies. 

  • Drive system-level integration, ensuring seamless collaboration across fields and geographies. 

  • Communicate complex technical decisions and trade-offs to senior collaborators with clarity and influence. 

  • Work hand-in-hand with Manufacturing, Quality, and Service teams to ensure design choices enable smooth scale-up and long-term reliability. 

Drive Innovation and Execution 

  • Serve as the hands-on technical authority for system definition, integration, and root-cause analysis. 
  • Guide technology down-selection, system verification, and early-stage prototyping efforts. 
  • Advance systems engineering practices — adopting model-based methods, simulation tools, and data-driven approaches. 
  • Champion new technologies and ideas that push the boundaries of what’s possible in qPCR instrumentation. 

Build and Develop the Team 

  • Recruit, mentor, and empower an extraordinary systems engineering team. 

  • Create a culture that values innovation, rigor, and collaborative problem-solving. 

  • Provide mentorship and growth opportunities for emerging technical leaders. 

  • Shape and scale systems engineering excellence across the broader R&D organization. 

 

What You Bring 

  • 8+ years of experience in systems engineering or multi-functional product development for life science or diagnostic instruments. 

  • Proven record of leading system integration across hardware, software, and consumables — from concept to launch. 

  • Demonstrated success managing and developing successful technical teams. 

  • Strong experience working in regulated environments (ISO 13485, FDA QSR, CE-IVD). 

  • Ability to partner strategically with Product Management and business leaders to translate vision into executable roadmaps. 

  • Deep understanding of systems engineering principles and broad technical fluency across mechanical, electrical, software, and assay domains. 

  • Excellent communication and influencing skills; comfortable communicating complex ideas to both engineers and executives. 

 

Education 

  • Bachelor’s, Master’s, or Ph.D. in Engineering (Mechanical, Electrical, Systems, or Software) or Applied Physics; advanced degree preferred. 

Locations

  • Singapore, Singapore

Salary

Estimated Salary Rangemedium confidence

90,000 - 150,000 USD / yearly

* This is an estimated range based on market data and may vary based on experience and qualifications.

Skills Required

  • system architectureintermediate
  • systems engineeringintermediate
  • model-based methodsintermediate
  • simulation toolsintermediate
  • data-driven approachesintermediate
  • multi-functional integrationintermediate

Required Qualifications

  • 8+ years experience in systems engineering or multi-functional product development (experience)

Responsibilities

  • Define and own system architecture
  • Translate user needs into requirements
  • Lead design trade-offs and risk analyses
  • Drive system-level integration
  • Mentor and build systems engineering team
  • Guide technology down-selection and prototyping

Target Your Resume for "Sr Manager, Systems Design Engineering" , Thermo Fisher Scientific

Get personalized recommendations to optimize your resume specifically for Sr Manager, Systems Design Engineering. Takes only 15 seconds!

AI-powered keyword optimization
Skills matching & gap analysis
Experience alignment suggestions

Check Your ATS Score for "Sr Manager, Systems Design Engineering" , Thermo Fisher Scientific

Find out how well your resume matches this job's requirements. Get comprehensive analysis including ATS compatibility, keyword matching, skill gaps, and personalized recommendations.

ATS compatibility check
Keyword optimization analysis
Skill matching & gap identification
Format & readability score

Answer 10 quick questions to check your fit for Sr Manager, Systems Design Engineering @ Thermo Fisher Scientific.

Quiz Challenge
10 Questions
~2 Minutes
Instant Score

Related Books and Jobs

No related jobs found at the moment.